Monckeberg’s sclerosis is a poorly understood condition associated with . Monckeberg’s sclerosis can coexist with atherosclerotic disease. Carlos Eduardo Barra Couri,1 Geruza Alves da Silva,1 José Antônio Baddini Martinez,1 Mönckeberg’s sclerosis (MS) is a degenerative and apparently .. The current concepts of the pathogenesis of Monckeberg-type arteriosclerosis. Mönckeberg sclerosis (MS) is a calcification of the me- dial layer of . ”Typical morphology of such calcifications in the early stages of the disease is linear de- posits along the . arteries in the absence of atherosclerotic plaque. Mayo Clin.

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Discrimination between calcified triticeous cartilage and calcified carotid atheroma on panoramic radiography. A review of the problem and a description of a patient monvkeberg involvement of peripheral, visceral and coronary arteries. In other cases, as in ours, the impairment is so diffuse, thick and calcified that arteriosclerosis makes clamping and arterial revascularization impossible, being determinant for the indication of primary amputation.

Artediosclerosis page was last edited on 30 Julyat Clinical and laboratory findings excluded any kind of rheumatologic disease such as dermatomyositis, scleroderma or systemic lupus erythematosus. Typically calcification is observed in the arteries of the upper and lower limb although it artdriosclerosis been seen in numerous other medium size arteries. Retrieved from ” https: Cardiac enzymes were elevated and suggestive of recent myocardial infarction creatinine phosphokinase CPK: Medial arterial calcification in diabetes and its relationship to neuropathy.

Monckeberg’s arteriosclerosis as a cause of lower limb critical ischemia: Anatomopathological test of the amputated limb showed ischemic necrosis, atherosclerosis with fibrous plaques and calcification of the medial layer in the femoral, popliteal and tibial arteries. It is, however, a benign condition as it does not involve the intimal layer of the artery, and the lumen is kept open by the rigid media.


Medial localization of mineralization-regulating proteins in association with Monckeberg’s sclerosis: Axial slices in which diffuse hyperdense lesions compatible with calcium deposits are visualized at the level of the abdominal aorta and its branches.

In monckebedg case, the femoral arteries were uninvolved, affording a second route.

Radiographic manifestations of Mönckeberg arteriosclerosis in the head and neck region

Its clinical significance and cause are not well understood and its relationship to atherosclerosis and other forms of vascular calcification are the subject of disagreement.

Vascular calcification and osteoporosis — the nature of the nexus.

The patient continued hemodynamically unstable, with important ischemia of lower limbs, quite possibly worsened by the use of vasopressors and the hypoperfusion state, so she required finally infracondylar amputation of the left lower limb.

Involvement of coronary, peripheral and visceral arteries by Monckeberg’s calcification was described by Lachman et al.

The authors declare that they have followed the protocols of their work center on the publication of patient data. Carotid artery stenosis Renal artery stenosis.

Monckeberg’s arteriosclerosis – Wikipedia

Am J Kidney Dis. Manuscript received August 29,accepted January 23, We conclude that, in cases of patients with arterioscleross obstructive arterial disease with undefined etiology and absence of traditional risk factors, it should be remembered that calcification of Monckeberg’s medial layer, despite being rare, can be the cause of peripheral vasculopathy.


Inflammation Arteritis Aortitis Buerger’s disease. Author information Article notes Copyright and License information Disclaimer. Since the condition does not involve primarily the intimal layer of the artery, the lumen is kept open by the rigid media and, therefore, luminal narrowing is not a direct consequence [ 1 – arterioscperosis ].

Slices of vessels and smooth muscle cells of the middle layer, focally replaced by hyalinized fibrous tissue presenting concentric dystrophic calcification.

To the best of artediosclerosis knowledge, soft tissue calcifications have never been described in such disease, especially in association with obstructive sleep apnea OSA. Most patients with medial calcinosis are asymptomatic, and it is usually an incidental finding, identified either clinically or on panoramic or periapical radiographs.

Generally, the pathogenesis of upper airway obstruction involves anatomic and neurological components. Rheumatol Int, 30pp. Cardiovasc Diabetol, 4pp.

Monckeberg’s arteriosclerosis as a cause of lower limb critical ischemia: case report

Accelerated atherosclerotic calcification and Monckeberg’s sclerosis: Arterioscler Thromb Vasc Biol. Best Pract Res Clin Rheumatol, 24pp. Extensive tortuous railroad track-type calcification in monckeebrg facial artery is noted in the soft tissue of the neck and cheek bilaterally arrows.

National Center for Biotechnology InformationU. Received May 21; Accepted Sep Published online Apr Support Center Support Center. Monckeberg’s Arteriosclerosis and Metabolic Bone Disease.