Request PDF on ResearchGate | On Feb 11, , Karl‐Heinz Maurer and others published Enzyme Technologies: Metagenomics, Evolution, Biocatalysis and. Enzyme technologies: metagenomics, evolution, biocatalysis, and biosynthesis 5 Enzyme Catalysis in the Synthesis of Active Pharmaceutical Ingredients. Enzyme technologies: metagenomics, evolution, biocatalysis, and Part B. Biocatalytic applications ; Enzyme catalysis in the synthesis of.

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Advancements in Enzyme Engineering Many worldwide corporations have recognized the bio-based technologies as one of the key drivers of sustainable growth.

Technology Prospecting on Enzymes: Application, Marketing and Engineering

According to a research report from Austrian Federal Environment Agency [ 7 ], about enzymes were used in food industry, 64 enzymes in technical application and 57 enzymes in feedstuff, of which 24 enzymes are used in three industrial sectors. Generally speaking, China’s enzyme products are not developed well in a sustainable way and cannot keep pace with superior product standards of many enzymes. Utilization of enzyme improvement tools therefore provides a feasible means to fine tuning for adaptability to industrial scale production.

In the past decades, many sectors of chemical industry were restrained from embracing enzyme technology, largely because enzymes were considered as being too delicate to survive the extreme conditions in real reaction vessels. Some recent developments and achievements in exploring new enzymes with outstanding properties will be briefly discussed in the following text. Pharmaceuticals, dietary supplement, biotransformation, diagnositics, food processing.

Securing maximum fermentability of the wort. The production and consumption capacity of enzymes in China are developed rapidly, which are increased more than two times from to Error! Organic synthesis industry Hydrolases, such as lipases, nitrilases, nitrile hydratases, esterases, amidases Acylation, deacylation, enantioseparation. Phytases Degrading evolutionn acid to release phosphorus, and liberating calcium, magnesium cations.

Enzyme Technologies: Metagenomics, Evolution, Biocatalysis and Biosynthesis

Bioenergy production tedhnologies demand was limited by the new legislative mandates for grain based ethanol. The enzyme industry is intent to develop this opportunity in China.


Food enzymes are mainly used in baking industry, fruit juice and cheese manufacturing, as well as wine making and brewing to improve their flavor, texture, digestibility, and nutritional value. Olempska-Beer [ 28 ] reviewed the microbial strains engineered for food enzyme production from a security point of view.

China’s policy makers have planned a large amount of budget on technology innovation and research on enzyme [ 44 ]. It plans to consume 5 million tons of ethanol between andwhich is nearly double that used during the previous five year period.

Oxidation of alcohols and oxygenation of C-H and C-C bonds. Proteases Reducing the protein in flour. Pectinases Degrading pectins which are structural polysaccharides present in the cell wall.

These applications include catalase in skin protection [ 32 ], laccase in hair dye [ 33 ], lipase to prevent treat skin rash or diaper rash [ 34 ], endoglycosidase and papain in toothpaste and mouthwash to whiten teeth, remove plaque and odor-causing deposits on teeth and gum tissue [ 34 ], and vitamin precursor and fatty alcohol and some enzymes coupled with polymeric molecules [ 35 ]. For example, diets based on cereals such as barley, rye and wheat are higher in non-starch polysaccharides NSPswhich can decrease the intestinal methane production when supplemented with NSP enzymes.

For example, only about types of enzymes are produced in China, which is much less product diversity than in developed countries. Removing the fuzz and microfibers to give the fabric a smoother and glossier appearance.

The related enzyme market is growing due to macro trends, such as urbanization and GDP increase. Industrial Enzyme Applications Enzymes technoloogies applied in various fields, including technical use, food manufacturing, animal nutrition, cosmetics, medication, and as tools for research and development. But in general, the processing aids are used during the manufacturing process of foodstuff, and do not have a technological function demand in the final food.

Albeit with lower market shares, about 50 small Chinese enzyme producers occupied large part of the feed enzymes. Several multinational companies have invested biocataoysis the enzyme industry in China.


Besides that, peroxidase is also used to prevent cosmetic formulations from bacterial attack for it can enzyyme the oxygen present in the contents. Ribosome display and related technologies: While the development of the second generation biofuels derived from cellulosic raw materials will be in favor of demand growth over a long time.

Western Europe would still occupy the largest producer of enzymes in the future ten years. Feed additive with the asterisk has obtained importation license. Enzymes are applied in various fields, including technical use, food manufacturing, animal nutrition, cosmetics, medication, and as tools for research and development.

Nat Chem Biol 5: Food processing Dairy industry Chymosin, lipases, lysozymes Cheese manufacturing.

Technology Prospecting on Enzymes: Application, Marketing and Engineering

National Center for Biotechnology InformationU. The exported volume of enzymes continues to grow year by year Error! Larcabal [ 37 ] reported that although subtilisin A removed light deposits more effectively, papain was slightly better with medium deposits and more effective with heavy deposits than subtilisin A. The use of enzymes in animal nutrition has an important role in current farming systems [ 22 ]. Nakano [ 64 ] developed a novel strategy in an array format for generation and screening of protein library by affinity selection or enzymatic activity.

But there is a problem that it is difficult to stop the enzyme to eat the skin, which may cause skin irritations. Clarifying cloudy juice, especially for apple juice. By accessing different locations such as volcanic vents, deep oceans beds, arctic tundra, etcthis method could help people to find more than a million previously unknown genes coding for novel enzymes.